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Serotonin Syndrome Symptom

     

Serotonin syndrome's symptoms and signs appear to result from stimulation of specific central and peripheral serotonin receptors, especially 5HT1a and 5HT2. Others-such as 5HT3 and 5HT4-may also be involved in causing GI symptoms and may affect dopaminergic transmission.

The Serotonin Syndrome is a potentially lethal condition caused by excessive serotonergic activity and is diagnosed by the presence of at least 3 of 10 symptoms: mental status changes (confusion, hypomania), agitation, myoclonus, hyperreflexia, diaphoresis, shivering, tremor, diarrhea, incoordination, and fever.

The symptoms of the serotonin syndrome are:

  • sweating
  • feeling drunk and dizzy
  • high body temperature
  • drowsiness
  • overreaction of the reflexes
  • clumsiness
  • restlessness
  • muscle contraction and relaxation in the jaw,
  • intoxication
  • muscle twitching
  • rigidity
  • euphoria
  • mental status changes
  • shivering
  • diarrhea
  • sustained rapid eye movement
  • loss of consciousness
  • rapid muscle contraction and relaxation in the ankle causing abnormal movements of the foot.

Serotonin Syndrome - Serotonin Syndrome Symptom

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